TBTC

TBTC is a selective agonist with the activity of improving behavioral deficits in Alzheimer's disease model mice. TBTC can effectively activate the heterodimerization of RXRα with LXRα or PPARγ. TBTC stimulates the expression of apoE, ABCA1, and ABCG1 genes and reduces Aβ content in cells and animal models[1].

Product Specifications

CAS Number

[213192-26-8]

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

RAR/RXR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tbtc.html

Smiles

O=C(OC)C1=C(SC2=C1CCC(C2)C(C)(C)C)N

Molecular Formula

C14H21NO2S

Molecular Weight

267.39

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Small molecule TBTC as a new selective retinoid X receptor α agonist improves behavioral deficit in Alzheimer's disease model mice

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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