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OXi8007

OXi8007 is a water-soluble phosphate proagent of OXi8006, a tubulin-binding compound.

Product Specifications

CAS Number

288847-41-6

UNSPSC

12352005

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/oxi8007.html

Purity

99.48

Solubility

DMSO : 90 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

O=P(OC1=CC(C(NC2=C3C=CC(OC)=C2)=C3C(C4=CC(OC)=C(C(OC)=C4)OC)=O)=CC=C1OC)(O[Na])O[Na]

Molecular Formula

C26H24NNa2O10P

Molecular Weight

587.42

References & Citations

[1]Strecker TE, et al. The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts. Cancer Lett. 2015 Dec 1;369 (1) :229-41.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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