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UCHL1-IN-1

UCHL1-IN-1 (Compound 46) is an inhibitor for Ubiquitin C-terminal Hydrolase L1 (UCHL1), with an IC50 of 5.1 μM. UCHL1-IN-1 can be used for cancer research[1].

Product Specifications

UNSPSC

12352005

Target

Deubiquitinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/uchl1-in-1.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

ClCC(NNC(CN(C1=CC=C(C=C1)Cl)C)=O)=O

Molecular Formula

C11H13Cl2N3O2

Molecular Weight

290.15

References & Citations

[1]Imhoff RD, et al. Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1. J Med Chem. 2024 Mar 15.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

UCHL1

Available Sizes

Frequently Asked Questions

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