UCHL1-IN-1
UCHL1-IN-1 (Compound 46) is an inhibitor for Ubiquitin C-terminal Hydrolase L1 (UCHL1), with an IC50 of 5.1 μM. UCHL1-IN-1 can be used for cancer research[1].
Product Specifications
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/uchl1-in-1.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
ClCC(NNC(CN(C1=CC=C(C=C1)Cl)C)=O)=O
Molecular Formula
C11H13Cl2N3O2
Molecular Weight
290.15
References & Citations
[1]Imhoff RD, et al. Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1. J Med Chem. 2024 Mar 15.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
UCHL1
Available Sizes
Curated Selection
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