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L-Glutamic acid-d3

L-Glutamic acid-d3 is the deuterium labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA) . L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

Product Specifications

CAS Number

203805-84-9

UNSPSC

12352211

Target

Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Purity

99.26

Solubility

H2O : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC(C([2H])([2H])C[C@@](N)([2H])C(O)=O)=O

Molecular Formula

C5H6D3NO4

Molecular Weight

150.15

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Isoform

AMPA Receptor

Available Sizes

Frequently Asked Questions

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