Monochlorobimane

Monochlorobimane (Chlorobimane) is a fluorescent dye (λex=380 nm, λem=470 nm) to measure glutathione (GSH) in cellular assays[1].

Product Specifications

CAS Number

[76421-73-3]

Product Name Alternative

Chlorobimane, mBBr

UNSPSC

12171500

Hazard Statement

H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/Monochlorobimane.html

Purity

99.86

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1N(C(C(C)=C2C)=O)N2C(CCl)=C1C

Molecular Formula

C10H11ClN2O2

Molecular Weight

226.66

Precautions

H315, H319, H335

References & Citations

[1]Kamencic H, et al. Monochlorobimane fluorometric method to measure tissue glutathione. Anal Biochem. 2000 Nov 1;286 (1) :35-7.|[2]Manuela D. Machado, et al. Assessment of cellular reduced glutathione content in Pseudokirchneriella subcapitata using monochlorobimane. Journal of Applied Phycology volume 24, pages1509–1516 (2012) .|[3]Fotopoulou T, et al. Design and Synthesis of Novel Antioxidant 2-Substituted-5,7,8-Trimethyl-1,4-Benzoxazine Hybrids: Effects on Young and Senescent Fibroblasts. Antioxidants (Basel) . 2024 Jun 29;13 (7) :798.