Human Cadherin-10 / CDH10 Protein, His Tag

Cadherins are a large family of cell –cell adhesion molecules involved in inter-cellular adhesion in a wide variety of cell types. In the nervous system, cadherins are known to be crucial to all stages of development, including the early separation of the neural tube from the ectoderm, the segregation of neurones and axons, and the formation of synapses. These molecules mediate calcium ion-dependent, homotypic primers designed using two highly conserved amino acid sequences in the cytoplasmic domain. One of the cadherins identified was cadherin-10. Cadherin-10 was first partially cloned from human brain, but its mRNA has also been shown to be present in mouse thymus (designated T2-cadherin), mouse testis, and in the developing brain and eye of mouse, rat, and chick.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 64.2 kDa. The protein migrates as 70-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.