AJ-76 (hydrochloride)
Product Specifications
UNSPSC Description
AJ-76 hydrochloride ((+)-AJ 76 hydrochloride) is an antagonist of dopamine autoreceptor with pKi values of 6.95, 6.67, 6.37, 6.21 and 6.07 for hD3, hD4, hD2S, hD2L and rD2 receptors, respectively.
Target Antigen
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/aj-76-hydrochloride.html
Purity
98.55
Solubility
DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)|Methanol : 25 mg/mL (ultrasonic)
Smiles
CCCN[C@H]1[C@@H](C)C2=C(C(OC)=CC=C2)CC1.Cl
Molecular Weight
269.816
References & Citations
[1]Kullingsjö H, et al. Effects of repeated administration of the preferential dopamine autoreceptor antagonist, (+)-AJ76, on locomotor activity and brain DA metabolism in the rat. Eur J Pharmacol. 1991 Dec 3;205(3):241-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101065/AJ-76-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101065/AJ-76-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
85378-82-1
Available Sizes
Curated Selection
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