Purified Anti-Human CD122 Antibody[TU27]
Product Specifications
Background
Functional IL-2 receptors can exist in two affinity states on cell surfaces, the high affinity complex consisting of heterotrimers of the alpha, beta, and gamma chains and the intermediate affinity complex comprising heterodimers of the beta and gamma chains. Individual beta chains and alpha chains exhibit low affinity IL-2 binding, and the gamma chain alone does not bind IL-2. In addition to their involvement in IL-2 mediated signal transduction, both the beta chain and gamma chain have been shown to be required for IL-15 mediated signaling. IL-2 R beta is a member of the cytokine receptor superfamily.
Abbreviation
CD122
Gene ID
3560
UniProt
P14784
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD122 protein
Target
P70; IL2RB; CD122; IL15RB; P70-75; IL-2Rβ; p75; IL-2RB; Interleukin-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; High affinity IL-2 receptor subunit beta; Interleukin-15 receptor subunit beta; p70-75 (p75) ; IL-2Rβ CD122 antigen; High affinity IL 2 receptor beta subunit; High affinity IL 2 receptor subunit beta; IL2 receptor; Interleukin 2 receptor beta; interleukin 2 receptor subunit beta; P70 75; P7075
Clonality
Monoclonal
Clone
TU27
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Signal Transduction; Stem Cells
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/vwpz9k
Product MSDS
https://789.bio/eb/eHp5t9
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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