(R)-Funapide
Product Specifications
UNSPSC Description
(R)-Funapide ((R)-TV 45070) is the less active R-enantiomer of Funapide. Funapide is a potent inhibitor of the sodium channel Nav1.7, Nav1.8 and other Nav channels expressed in the peripheral nervous system. Fornabil is an orally effective analgesic agent[1][2].
Target Antigen
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/r-funapide.html
Solubility
DMSO : 220 mg/mL (ultrasonic)
Smiles
O=C([C@@]12COC3=C1C=C(OCO4)C4=C3)N(CC5=CC=C(C(F)(F)F)O5)C6=C2C=CC=C6
Molecular Weight
429.35
References & Citations
[1]Sharan K Bagal, et al. Recent progress in sodium channel modulators for pain. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9.|[2]Kitano Y, et al. Inhibition of NaV1.7: the possibility of ideal analgesics. RSC Med Chem. 2022 Aug 1;13(8):895-920.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-16723A/R-Funapide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-16723A/R-Funapide-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1259933-15-7
Available Sizes
Curated Selection
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