AChE/BuChE-IN-4
Product Specifications
UNSPSC Description
AChE/BuChE-IN-4(compound 4a) is aorally activeandbrain-penetrantmultitarget-directedAChE/BuChEinhibitor againstAChEandBuChE, with theIC50of 2.08 and 7.41 μM[1].
Target Antigen
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-buche-in-4.html
Solubility
DMSO : ≥ 125 mg/mL
Smiles
NC1=NC=CC(NCC2CCN(CC2)CC3=CC=CC=C3)=N1
Molecular Weight
297.40
References & Citations
[1]Conceição RAD, et al. Structure-based design of new N-benzyl-piperidine derivatives as multitarget-directed AChE/BuChE inhibitors for Alzheimer's disease [published online ahead of print, 2023 Oct 5]. J Cell Biochem. 2023;10.1002/jcb.30483.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155349/AChE-BuChE-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155349/AChE-BuChE-IN-4-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1997158-25-4
Available Sizes
Curated Selection
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