Butylated hydroxytoluene

Butylated hydroxytoluene is an antioxidant widely used in foods and in food-related products[1]. Butylated hydroxytoluene is a Ferroptosis inhibitor[2].

Product Specifications

CAS Number

[128-37-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H360, H373, H410

Target

Endogenous Metabolite; Ferroptosis

Type

Reference compound

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/butylated-hydroxytoluene.html

Purity

99.99

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=C(C(C)(C)C)C=C(C)C=C1C(C)(C)C

Molecular Formula

C15H24O

Molecular Weight

220.36

Precautions

H302, H315, H319, H360, H373, H410

References & Citations

[1]Babich H, et al. Butylated hydroxytoluene (BHT) : a review. Environ Res. 1982 Oct;29 (1) :1-29.|[2]Umemura T, et al. Butylhydroxytoluene (BHT) increases susceptibility of transgenic rasH2 mice to lung carcinogenesis. J Cancer Res Clin Oncol. 2001 Oct;127 (10) :583-90.|[3]Stockwell BR, et al. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. ell. 2017 Oct 5;171 (2) :273-285.