Yp537 (TFA)

Yp537 TFA is an estrogen receptor (ER) inhibitor that blocks dimerization of the human estrogen receptor[1].

Product Specifications

Product Name Alternative

Anti-estrogen (TFA)

UNSPSC

12352209

Target

Estrogen Receptor/ERR

Type

Peptides

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/yp537-tfa.html

Purity

95.96

Solubility

H2O : 9.09 mg/mL (ultrasonic;adjust pH to 8 with NaOH)

Smiles

SC[C@H](N)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O)=O)=O)CC2=CC=C(C=C2)OP(O)(O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O

Molecular Formula

C66H105F3N13O24PS

Molecular Weight

1584.65

References & Citations

[1]Arnold SF, et al. An antiestrogen: a phosphotyrosyl peptide that blocks dimerization of the human estrogen receptor. Proc Natl Acad Sci U S A. 1995 Aug 1;92 (16) :7475-9.