KIF18A-IN-11
KIF18A-IN-11 (Compound 13) is a potent KIF18A inhibitor, with IC50 values of less than 100 nM in OVCAR3 and MDA-MB-157 cells. KIF18A-IN-11 can be used for the research of cancer[1].
Product Specifications
UNSPSC
12352005
Target
Kinesin; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kif18a-in-11.html
Smiles
O=C(C1=C(C=C(C2=C1CCC2)NS(=O)(CCO)=O)N3CCC4(CC4)CC3)NC5CN=CC(N6CCC(F)(CC6)F)=N5
Molecular Formula
C28H38F2N6O4S
Molecular Weight
592.70
References & Citations
[1]Liu B, et al. Kif18a inhibitor. WO2024067465A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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