Hemokinin 1, human
Hemokinin 1, human is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human can produces an opioid-independent analgesia[1][2].
Product Specifications
CAS Number
491851-53-7
UNSPSC
12352209
Target
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hemokinin-1-human.html
Purity
98.11
Solubility
10 mM in DMSO
Smiles
CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CO)NC([C@H](C)NC([C@H](CCCCN)NC(CNC([C@@H](N)[C@H](O)C)=O)=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O
Molecular Formula
C54H84N14O14S
Molecular Weight
1185.40
References & Citations
[1]Cai-Yun Fu, et al. Hemokinin-1 (4-11) -induced analgesia selectively up-regulates δ-opioid receptor expression in mice. PLoS One|[2]Francesca Bellucci, et al. Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. Br J Pharmacol. 2002 Jan;135 (1) :266-74.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
NK1R; NK2R; NK3R
Available Sizes
Frequently Asked Questions
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