Hemokinin 1, human

Hemokinin 1, human is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human can produces an opioid-independent analgesia[1][2].

Product Specifications

CAS Number

[491851-53-7]

UNSPSC

12352209

Target

Neurokinin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hemokinin-1-human.html

Purity

98.11

Solubility

10 mM in DMSO

Smiles

CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CO)NC([C@H](C)NC([C@H](CCCCN)NC(CNC([C@@H](N)[C@H](O)C)=O)=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O

Molecular Formula

C54H84N14O14S

Molecular Weight

1185.40

References & Citations

[1]Cai-Yun Fu, et al. Hemokinin-1 (4-11) -induced analgesia selectively up-regulates δ-opioid receptor expression in mice. PLoS One|[2]Francesca Bellucci, et al. Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. Br J Pharmacol. 2002 Jan;135 (1) :266-74.