Carbamazepine-d4
Carbamazepine-d4 (CBZ-d4) is the deuterium labeled Carbamazepine. Carbamazepine is an orally active pressure-sensitive sodium ion channel blocker with an IC50 of 131 μM. Carbamazepine blocks voltage gated Na+, Ca2+, and K+ channels, and is also a HDAC inhibitor (IC50: 2 μM). Carbamazepine is an anticonvulsant and can be used for research of epilepsy and neuropathic pain.
Product Specifications
Product Name Alternative
CBZ-d4; NSC 169864-d4
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Others
Purity
99.72
Smiles
O=C(N1C2=CC=CC=C2C=CC3=C([2H])C([2H])=C([2H])C([2H])=C31)N
Molecular Formula
C15H8D4N2O
Molecular Weight
240.29
References & Citations
[1]Russak, et sl. Impact of deuterium substitution on the pharmacokinetics of pharmaceuticals. Annals of Pharmacotherapy 53.2 (2019) : 211-236.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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