N-Formyl-Met-Leu-Phe-Lys
N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively[1].
Product Specifications
CAS Number
[67247-11-4]
Product Name Alternative
FMLFK
UNSPSC
12352209
Target
Formyl Peptide Receptor (FPR)
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/n-formyl-met-leu-phe-lys.html
Purity
99.83
Solubility
DMSO : 22.22 mg/mL (ultrasonic; adjust pH to 3 with 1M HCl)
Smiles
NCCCC[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)NC([C@H](CC(C)C)NC([C@H](CCSC)NC=O)=O)=O)=O
Molecular Formula
C27H43N5O6S
Molecular Weight
565.73
References & Citations
[1]He HQ, et al. Structural determinants for the interaction of formyl peptide receptor 2 with peptide ligands. J Biol Chem. 2014 Jan 24;289 (4) :2295-306.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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