GSK682753A
GSK682753A is a selective and highly potent inverse agonist of the epstein-barr virus-induced receptor 2 (EBI2) with an IC50 of 53.6 nM.
Product Specifications
CAS Number
[1334294-76-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
EBI2/GPR183
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/GSK682753A.html
Purity
99.90
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1OC2(CCN(C(/C=C/C3=CC=C(Cl)C=C3)=O)CC2)CN1CC4=CC=C(Cl)C(Cl)=C4
Molecular Formula
C23H21Cl3N2O3
Molecular Weight
479.78
Precautions
H302, H315, H319, H335
References & Citations
[1]Benned-Jensen T, et al. Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist. J Biol Chem. 2011 Aug 19;286 (33) :29292-302.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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