Anticancer agent 170

Anticancer agent 170 (compound 3a) is a keton derivative of Deguelin (HY-13425), and shows potency anti-cancer activity against A549, with the IC50 of 6.62 μM[1].

Product Specifications

CAS Number

[24126-98-5]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-170.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=C(CC(C2=CC=C(O)C=C2O)=O)C=C1OC

Molecular Formula

C16H16O5

Molecular Weight

288.30

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]John Alfon P. Francisco, et al. Inhibitory Effects of B-, C-, and E-Ring-Truncated Deguelin Derivatives Against A549, HCT116, and MCF-7 Cancer Cells. ACS Omega 2023, 8, 45, 43109–43117