HDHODH-IN-1
HDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor. hDHODH-IN-1 has anti-inflammatory effect[1].
Product Specifications
CAS Number
1173715-42-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Dihydroorotate Dehydrogenase; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hdhodh-in-1.html
Purity
99.90
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
C/C(O)=C(C#N)/C(NC1=CC=C(C2=CC=CC=C2)C=C1)=O
Molecular Formula
C17H14N2O2
Molecular Weight
278.31
Precautions
H302, H315, H319
References & Citations
[1]Shih KC, et al. Development of a human dihydroorotate dehydrogenase (hDHODH) pharma-similarity index approach with scaffold-hopping strategy for the design of novel potential inhibitors. PLoS One. 2014 Feb 4;9 (2) :e87960.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC470009-500 1x 500 µL
MART-1 / Melan-A (M2-7C10), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682316-500 1x 500 µL
Cdk2 / p34cdc2 Serine-Threonine Kinase (AN4.3), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC042409-500 1x 500 µL
STAT3 / Signal Transducer and Activator of Transcription 3 (STAT3/2409), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470769-500 1x 500 µL
P27 / KIP1 (KIP1/769), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680329-100 1x 100 µL
Small Cell Lung Cancer (SCLC) (MOC-52), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details