HDHODH-IN-1
HDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor. hDHODH-IN-1 has anti-inflammatory effect[1].
Product Specifications
CAS Number
[1173715-42-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Dihydroorotate Dehydrogenase; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hdhodh-in-1.html
Purity
99.90
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
C/C(O)=C(C#N)/C(NC1=CC=C(C2=CC=CC=C2)C=C1)=O
Molecular Formula
C17H14N2O2
Molecular Weight
278.31
Precautions
H302, H315, H319
References & Citations
[1]Shih KC, et al. Development of a human dihydroorotate dehydrogenase (hDHODH) pharma-similarity index approach with scaffold-hopping strategy for the design of novel potential inhibitors. PLoS One. 2014 Feb 4;9 (2) :e87960.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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