Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Alpha-Mangostin (Standard)

Alpha-Mangostin (Standard) is the analytical standard of alpha-Mangostin. This product is intended for research and analytical applications. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM.

Product Specifications

CAS Number

6147-11-1

Product Name Alternative

α-Mangostin (Standard)

UNSPSC

12352005

Hazard Statement

H301

Target

Apoptosis; Bacterial; Fungal; Reactive Oxygen Species (ROS) ; Reference Standards; Virus Protease

Type

Reference Standards

Related Pathways

Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/alpha-mangostin-standard.html

Purity

99.44

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(OC3=C1C(C/C=C(C)\C)=C(OC)C(O)=C3)C=C(O)C(C/C=C(C)\C)=C2O

Molecular Formula

C24H26O6

Molecular Weight

410.46

Precautions

H301

References & Citations

[1]Kim HJ, et al. Discovery of α-mangostin as a novel competitive inhibitor against mutant isocitrate dehydrogenase-1. Bioorg Med Chem Lett. 2015 Dec 1;25 (23) :5625-31.|[2]Lee HN, et al. Antitumor and apoptosis-inducing effects of α-mangostin extracted from the pericarp of the mangosteen fruit (Garcinia mangostana L.) in YD-15 tongue mucoepidermoid carcinoma cells. Int J Mol Med. 2016 Apr;37 (4) :939-48.

Shipping Conditions

Room Temperature

Storage Conditions

4°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Clinical Information

Phase 2

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

FYTTD1 (NM_001011537) Human Over-expression Lysate
LC432168 20 µg

FYTTD1 (NM_001011537) Human Over-expression Lysate

Sign In for Pricing
View Details
M-CSF (CSF1) (NM_172210) Human Over-expression Lysate
LC403534 20 µg

M-CSF (CSF1) (NM_172210) Human Over-expression Lysate

Sign In for Pricing
View Details
S100A4 / Metastasin / Calvasculin (Marker of Tumor Metastasis) (rS100A4/1481), 0.2mg/mL
BNUB3186-100 1x 100 µL

S100A4 / Metastasin / Calvasculin (Marker of Tumor Metastasis) (rS100A4/1481), 0.2mg/mL

Sign In for Pricing
View Details
Tissue Total RNA, Ovary: left
CR562145 5 µg

Tissue Total RNA, Ovary: left

Sign In for Pricing
View Details
Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF647 conjugate, 0.1mg/mL
BNC471968-100 1x 100 µL

Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Znrf1 Mouse Gene Knockout Kit (CRISPR)
KN520129 1 Kit

Znrf1 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details