CD300a/LMIR1, Human (HEK293, Fc-His)
Product Specifications
UNSPSC Description
CD300a/LMIR1 Protein, an inhibitory receptor, potentially diminishes cytolytic activity in NK cells and suppresses mast cell degranulation. It serves as a negative regulator in MYD88-mediated TLR signaling, activating PTPN6 but not TRIF. Upon tyrosine phosphorylation, CD300a/LMIR1 engages with PTN6/SHP-1, PTPN11/SHP-2, and INPP5D, showcasing its multifaceted involvement in immune regulation and cellular responses. CD300a/LMIR1 Protein, Human (HEK293, Fc-His) is the recombinant human-derived CD300a/LMIR1 protein, expressed by HEK293 , with C-hFc, C-6*His labeled tag.
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/cd300a-protein-human-hek-293-fc-his.html
Smiles
LSKCRTVAGP VGGSLSVQCP YEKEHRTLNK YWCRPPQIFL CDKIVETKGS AGKRNGRVSI RDSPANLSFT VTLENLTEED AGTYWCGVDT PWLRDFHDPV VEVEVSVFPA STSMTPASIT AAKTSTITTA FPPVSSTTLF AVGATHSASI QEETEEVVNS Q
Molecular Weight
Approximately 75.0 kDa
Shipping Conditions
Room temperature
Curated Selection
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