VGX-1027
VGX-1027 is an orally active isoxazole compound that exhibits various immunomodulatory properties. VGX-1027 targets macrophages, reducing the production of the proinflammatory mediators TNF-α, IL-1β, IL-10. VGX-1027 has antidiabetogenic effects by limiting cytokine-mediated immunoinflammatory events[1][2][3].
Product Specifications
CAS Number
6501-72-0
Product Name Alternative
GIT 27
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Interleukin Related; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/VGX-1027.html
Purity
99.67
Solubility
DMSO : ≥ 56 mg/mL
Smiles
O=C(O)CC1CC(C2=CC=CC=C2)=NO1
Molecular Formula
C11H11NO3
Molecular Weight
205.21
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
IL-1; IL-10; TNFRSF5/CD40
Available Sizes
Frequently Asked Questions
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