Nadolol (Standard)

Nadolol (Standard) is the analytical standard of Nadolol. This product is intended for research and analytical applications. Nadolol (SQ-11725) is a non-selective and orally active β-adrenergic receptors blocker and is a substrate of organic anion transporting polypeptide 1A2 (OATP1A2) . Nadolol has the the potential for high blood pressure, angina pectoris and vascular headaches research[1][2][3].

Product Specifications

CAS Number

[42200-33-9]

Product Name Alternative

SQ-11725 (Standard)

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Adrenergic Receptor; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/nadolol-standard.html

Purity

99.76

Smiles

OC1CC2=C(C(OCC(O)CNC(C)(C)C)=CC=C2)CC1O

Molecular Formula

C17H27NO4

Molecular Weight

309.40

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Johannes C von Alvensleben, et al. Nadolol for Treatment of Supraventricular Tachycardia in Infants and Young Children. Pediatr Cardiol. 2017 Mar;38 (3) :525-530.|[2]Osamu Abe, et al. Role of (-) -Epigallocatechin Gallate in the Pharmacokinetic Interaction Between Nadolol and Green Tea in Healthy Volunteers. Eur J Clin Pharmacol. 2018 Jun;74 (6) :775-783.|[3]O Vegas, et al. Effects of Antalarmin and Nadolol on the Relationship Between Social Stress and Pulmonary Metastasis Development in Male OF1 Mice. Behav Brain Res. 2009 Dec 14;205 (1) :200-6.