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(10E,12E) -9-Oxo-10,12-octadecadienoic acid

(10E,12E) -9-Oxo-10,12-octadecadienoic acid (9-oxo-ODA) is a PPARα agonist that can be isolated from the basidiomycete Gomphus floccosus. (10E,12E) -9-Oxo-10,12-octadecadienoic acid enhances fatty acid oxidation through PPARα activation, thereby inhibiting triglyceride accumulation. (10E,12E) -9-Oxo-10,12-octadecadienoic acid also has antifungal (Fungal) activity[1][2].

Product Specifications

CAS Number

54232-58-5

Product Name Alternative

9-oxo-ODA

UNSPSC

12352211

Hazard Statement

H225-H319

Target

Fungal; PPAR

Type

Natural Products

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/10e-12e-9-oxo-10-12-octadecadienoic-acid.html

Solubility

10 mM in DMSO

Smiles

CCCCC/C=C/C=C/C(CCCCCCCC(O)=O)=O

Molecular Formula

C18H30O3

Molecular Weight

294.43

Precautions

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501

References & Citations

[1]Cantrell CL, et al. Isolation and identification of antifungal fatty acids from the basidiomycete Gomphus floccosus. J Agric Food Chem. 2008 Jul 9;56 (13) :5062-8.|[2]Kim YI, et al. Potent PPARα activator derived from tomato juice, 13-oxo-9,11-octadecadienoic acid, decreases plasma and hepatic triglyceride in obese diabetic mice. PLoS One. 2012;7 (2) :e31317.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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