DL-alpha-Tocopherol

DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1].

Product Specifications

CAS Number

[10191-41-0]

Product Name Alternative

DL-α-Tocopherol

UNSPSC

12352005

Hazard Statement

H317

Target

Apoptosis; DNA/RNA Synthesis; Ferroptosis

Type

Natural Products

Related Pathways

Apoptosis; Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dl-alpha-tocopherol.html

Purity

99.84

Solubility

DMSO : 20 mg/mL (ultrasonic) |Ethanol : ≥ 100 mg/mL

Smiles

CC1=C2C(CCC(CCCC(C)CCCC(C)CCCC(C)C)(C)O2)=C(C)C(O)=C1C

Molecular Formula

C29H50O2

Molecular Weight

430.71

Precautions

H317

References & Citations

[1]Kondo S, et al. Protective effect of dl-alpha-tocopherol on the cytotoxicity of ultraviolet B against human skin fibroblasts in vitro. Photodermatol Photoimmunol Photomed. 1990 Aug;7 (4) :173-7.|[2]Triggs WJ, et al., Effect of [dl]-alpha-tocopherol on FeCl2-induced lipid peroxidation in rat amygdala. Neurosci Lett. 1994 Oct 10;180 (1) :33-6.|[3]Sigounas G, et al., dl-alpha-tocopherol induces apoptosis in erythroleukemia, prostate, and breast cancer cells. Nutr Cancer. 1997;28 (1) :30-5.