VX-166
VX-166, a pan caspase inhibitor, can be used for the research of Non- Alcoholic Fatty Liver Disease (NAFLD), nonalcoholic steatohepatitis (NASH), alcoholic steatohepatitis (ASH), and other diseases involving fibrosis, steatosis, or inflammation of the liver[1].
Product Specifications
CAS Number
800408-39-3
UNSPSC
12352005
Target
Caspase
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/vx-166.html
Smiles
FC(C(F)=CC(F)=C1F)=C1OCC([C@H](CC(O)=O)NC([C@@H](N2C(C(NC(OC)=O)=CC=C2)=O)CC)=O)=O
Molecular Formula
C22H21F4N3O8
Molecular Weight
531.41
References & Citations
[1]John Pollard, et al. Treatment of liver diseases with a caspase inhibitor. Patent WO2010120880A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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