MrgprX2 antagonist-2

MrgprX2 antagonist-2 is an MrgprX2 antagonist extracted from patent WO2021092262A1, example E163. MrgprX2 antagonist-2 can be used for the research of inflammatory disorders of the skin[1].

Product Specifications

CAS Number

[2642346-30-1]

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Mas-related G-protein-coupled Receptor (MRGPR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mrgprx2-antagonist-2.html

Concentration

10mM

Purity

99.20

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(F)(F)[C@H](O)CN(CC)C(NC1=CC(OC2=CC(F)=CC(F)=C2)=CC=N1)=O

Molecular Formula

C17H16F5N3O3

Molecular Weight

405.32

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]CEVIKBAS F, et, al. Mrgprx2 antagonists and uses thereof. WO2021092262A1.|[2]Porebski G, et, al. Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions. Front Immunol. 2018 Dec 20;9:3027.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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