MrgprX2 antagonist-2
Product Specifications
UNSPSC Description
MrgprX2 antagonist-2 is an MrgprX2 antagonist extracted from patent WO2021092262A1, example E163. MrgprX2 antagonist-2 can be used for the research of inflammatory disorders of the skin[1].
Target Antigen
Mas-related G-protein-coupled Receptor (MRGPR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mrgprx2-antagonist-2.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(F)(F)[C@H](O)CN(CC)C(NC1=CC(OC2=CC(F)=CC(F)=C2)=CC=N1)=O
Molecular Weight
405.32
References & Citations
[1]CEVIKBAS F, et, al. Mrgprx2 antagonists and uses thereof. WO2021092262A1.|[2]Porebski G, et, al. Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions. Front Immunol. 2018 Dec 20;9:3027.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145192/MrgprX2-antagonist-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145192/MrgprX2-antagonist-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2642346-30-1
Available Sizes
Curated Selection
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