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KCNN4 (SK4) rabbit pAb

Potassium calcium-activated channel subfamily N member 4 (KCNN4) Homo sapiens The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Potassium calcium-activated channel subfamily N member 4 (KCNN4) Homo sapiens The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq, Jul 2008]

Synonyms

KCNN4; IK1; IKCA1; KCA4; SK4; Intermediate conductance calcium-activated potassium channel protein 4; SK4; SKCa 4; SKCa4; IKCa1; IK1; KCa3.1; KCa4; Putative Gardos channel

Gene ID

3783

UniProt

O15554

Cellular Locus

Cell membrane ; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse

Reactivity

Human; Rat; Mouse

Immunogen

Synthetic Peptide of KCNN4 (SK4) AA range: 177-227

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF

Validated Applications

WB,IHC,IF

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:1000-2000, IHC 1:50-100

Molecular Weight

50kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES20693-1.pdf

Observed Molecular Weight

50 kD

Subcellular Location

Cell membrane ; Multi-pass membrane protein .

Other Product Names

KCNN4; IK1; IKCA1; KCA4; SK4; Intermediate conductance calcium-activated potassium channel protein 4; SK4; SKCa 4; SKCa4; IKCa1; IK1; KCa3.1; KCa4; Putative Gardos channel

Gene ID (Human)

3783

SwissProt (Human)

O15554

Available Sizes

Curated Selection

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