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ENOS (Phospho-Ser1179) rabbit pAb

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],

Product Specifications

Background

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

UniProt

P29474

Swiss Prot

P29474

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human eNOS (Phospho-Ser1179)

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; WB

Concentration

1 mg/ml

Dilution

IHC-p 1:50-200, WB 1:500-2000

Molecular Weight

130-140kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

130-140kD

Fragment

IgG

Subcellular Location

Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.

Other Product Names

Nitric oxide synthase, endothelial (EC 1.14.13.39; Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; eNOS; NOS type III; NOSIII)

Gene ID (Human)

4846

Available Sizes

Curated Selection

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