Tricyclic cytosine tC
Tricyclic cytosine tC is a fluorescent base analogue that can be used as a fluorescent probe in nucleic acid-containing systems. The excitation wavelength is 385 nm and the emission wavelength is 505 nm[1][2].
Product Specifications
CAS Number
1174063-74-1
UNSPSC
12352005
Target
DNA Stain
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tricyclic-cytosine-tc.html
Solubility
10 mM in DMSO
Smiles
O=C1N([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C=C(SC3=CC=CC=C3N4)C4=N1
Molecular Formula
C15H15N3O5S
Molecular Weight
349.36
References & Citations
[1]Sandin P, Lincoln P, Brown T, Wilhelmsson LM. Synthesis and oligonucleotide incorporation of fluorescent cytosine analogue tC: a promising nucleic acid probe. Nat Protoc. 2007;2 (3) :615-23. |[2]Manetto A, et al. tC, tCo and tCnitro: Tricyclic Cytosine Probes of DNA and RNA Structure. The Glen Report. 2010, 22 (13) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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