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Tricyclic cytosine tC

Tricyclic cytosine tC is a fluorescent base analogue that can be used as a fluorescent probe in nucleic acid-containing systems. The excitation wavelength is 385 nm and the emission wavelength is 505 nm[1][2].

Product Specifications

CAS Number

1174063-74-1

UNSPSC

12352005

Target

DNA Stain

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/tricyclic-cytosine-tc.html

Solubility

10 mM in DMSO

Smiles

O=C1N([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C=C(SC3=CC=CC=C3N4)C4=N1

Molecular Formula

C15H15N3O5S

Molecular Weight

349.36

References & Citations

[1]Sandin P, Lincoln P, Brown T, Wilhelmsson LM. Synthesis and oligonucleotide incorporation of fluorescent cytosine analogue tC: a promising nucleic acid probe. Nat Protoc. 2007;2 (3) :615-23. |[2]Manetto A, et al. tC, tCo and tCnitro: Tricyclic Cytosine Probes of DNA and RNA Structure. The Glen Report. 2010, 22 (13) .

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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