DOTA-CXCR4-L
Product Specifications
UNSPSC Description
DOTA-CXCR4-L is a CXCR4 targeting peptide. DOTA-CXCR4-L can be used in the study of cancers, including glioblastoma and triple-negative breast cancer[1].
Target Antigen
CXCR; Radionuclide-Drug Conjugates (RDCs)
Type
Peptides
Related Pathways
Antibody-drug Conjugate/ADC Related;GPCR/G Protein;Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dota-cxcr4-l.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H]1CC2=CC3=C(C=C2)C=CC=C3)[C@H](CCCNC(N)=N)NC([C@@H](CCCNC(C4=CN=C(C=C4)NNC(CN5CCN(CCN(CCN(CC5)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)N(C)C([C@@H](CC6=CC=C(O)C=C6)NC(CNC1=O)=O)=O)=O
Molecular Weight
1223.34
References & Citations
[1]Luna-Gutiérrez M, et al. Preclinical evaluation of the theranostic 68 Ga/177 Lu-[DOTA-CXCR4-L] pair [C]//Trends in Radiopharmaceuticals (ISTR-2019). Proceedings of an International Symposium. Programme and Abstracts. 2020.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P5297/DOTA-CXCR4-L-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P5297/
Clinical Information
No Development Reported
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