PD-0299685

PD-0299685 is a potent Ca2+ channel α2δ ligand. PD-0299685 is promising for research of refractory genito-urinary pain and interstitial cystitis/bladder pain syndrome[1][2].

Product Specifications

CAS Number

[313651-33-1]

UNSPSC

12352211

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pd-0299685.html

Smiles

CCC[C@@H](C)C[C@H](CN)CC(O)=O

Molecular Formula

C10H21NO2

Molecular Weight

187.28

References & Citations

[1]Nickel JC, et al. Investigation of a Ca2+ channel α2δ ligand for the treatment of interstitial cystitis: results of a randomized, double-blind, placebo controlled phase II trial. J Urol. 2012 Sep;188 (3) :817-23.|[2]Nickel J C, et al. 821 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE IIA TRIAL OF A CA2+ CHANNEL α2Δ LIGAND, PD-0299685, FOR THE TREATMENT OF INTERSTITIAL CYSTITIS/BLADDER PAIN SYNDROME[J]. The Journal of Urology, 2012, 187 (4S) : e335-e335.