PD-0299685
PD-0299685 is a potent Ca2+ channel α2δ ligand. PD-0299685 is promising for research of refractory genito-urinary pain and interstitial cystitis/bladder pain syndrome[1][2].
Product Specifications
CAS Number
313651-33-1
UNSPSC
12352211
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pd-0299685.html
Smiles
CCC[C@@H](C)C[C@H](CN)CC(O)=O
Molecular Formula
C10H21NO2
Molecular Weight
187.28
References & Citations
[1]Nickel JC, et al. Investigation of a Ca2+ channel α2δ ligand for the treatment of interstitial cystitis: results of a randomized, double-blind, placebo controlled phase II trial. J Urol. 2012 Sep;188 (3) :817-23.|[2]Nickel J C, et al. 821 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE IIA TRIAL OF A CA2+ CHANNEL α2Δ LIGAND, PD-0299685, FOR THE TREATMENT OF INTERSTITIAL CYSTITIS/BLADDER PAIN SYNDROME[J]. The Journal of Urology, 2012, 187 (4S) : e335-e335.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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