5’-O- (4,4’-Dimethoxytrityl) -2’-O-methyluridine

5’-O- (4,4’-Dimethoxytrityl) -2’-O-methyluridine is a uridine analog. 5’-O- (4,4’-Dimethoxytrityl) -2’-O-methyluridine is a key precursor for the synthesis of oligodeoxynucleotides containing a cyclic structure[1][2].

Product Specifications

CAS Number

[103285-22-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Intermediate; Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Others

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-o-4-4-dimethoxytrityl-2-o-methyluridine.html

Purity

98.03

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COC(C3=CC=C(OC)C=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5

Molecular Formula

C31H32N2O8

Molecular Weight

560.59

Precautions

H302, H315, H319, H335

References & Citations

[1]Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20 (5) :218-25.|[2]Sekine M, et al. Synthesis and properties of oligodeoxynucleotides incorporating a conformationally rigid uridine unit having a cyclic structure at the 5'-terminal site. J Org Chem. 2000 Jun 16;65 (12) :3571-8.