KHK-IN-5

KHK-IN-5 (Compound 18) is a KHK inhibitor. KHK-IN-5 can be used for the research of nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and type 2 diabetes (T2DM) [1].

Product Specifications

CAS Number

[3043939-40-5]

UNSPSC

12352005

Target

Ketohexokinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/khk-in-5.html

Smiles

N#CC(C(C(F)F)=CC(N1C[C@@]2([H])[C@@](CNC2)([H])C1)=N3)=C3NC4=C(C=CC=C4)SC

Molecular Formula

C20H21F2N5S

Molecular Weight

401.48

References & Citations

[1]Sabnis RW. Novel Cyanopyridine Compounds as KHK Inhibitors for Treating NAFLD, NASH, and Type II Diabetes. ACS Med Chem Lett. 2024 Jul 23;15 (8) :1191-1192.