KHK-IN-5
KHK-IN-5 (Compound 18) is a KHK inhibitor. KHK-IN-5 can be used for the research of nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and type 2 diabetes (T2DM) [1].
Product Specifications
CAS Number
[3043939-40-5]
UNSPSC
12352005
Target
Ketohexokinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/khk-in-5.html
Smiles
N#CC(C(C(F)F)=CC(N1C[C@@]2([H])[C@@](CNC2)([H])C1)=N3)=C3NC4=C(C=CC=C4)SC
Molecular Formula
C20H21F2N5S
Molecular Weight
401.48
References & Citations
[1]Sabnis RW. Novel Cyanopyridine Compounds as KHK Inhibitors for Treating NAFLD, NASH, and Type II Diabetes. ACS Med Chem Lett. 2024 Jul 23;15 (8) :1191-1192.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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