Inosine (Standard)
Inosine (Standard) is the analytical standard of Inosine. This product is intended for research and analytical applications. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors[1][2][3]. In Vitro:Inosine dose-dependently stimulates cAMP production mediated through the A2AR[2]. Inosine dose-dependently induces hA2AR-mediated ERK1/2 phosphorylation[2]. Inosine (100 μM; 24 hours) reduces oxidative stress in MES 23.5 cells cultured with astrocytes[3]. In Vivo:Inosine (10-100 mg/kg; i.p.) exhibits antinociceptive effect in mice[2].
Product Specifications
CAS Number
58-63-9
UNSPSC
12352005
Target
Adenosine Receptor; Endogenous Metabolite; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/inosine-standard.html
Purity
99.93
Smiles
O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CNC3=O
Molecular Formula
C10H12N4O5
Molecular Weight
268.23
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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