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Crocin II

Crocin II is isolated from the fruit of Gardenia jasminoides with antioxidant, anticancer, and antidepressant activity. Crocin II inhibits NO production with an IC50 value of 31.1 μM. Crocin II suppresses the expressions of protein and m-RNA of iNOS and COX-2[1].

Product Specifications

CAS Number

[55750-84-0]

UNSPSC

12352005

Target

COX; Endogenous Metabolite; NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/crocin-ii.html

Purity

99.04

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O[C@@H]([C@H](O)[C@H]1O)[C@H](O[C@H]1OC(/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C(O[C@@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO)=O)=O)CO[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO

Molecular Formula

C38H54O19

Molecular Weight

814.82

References & Citations

[1]Hong YJ, et al. Anti-inflammatory activities of crocetin derivatives from processed Gardenia jasminoides. Arch Pharm Res. 2013 Aug;36 (8) :933-40.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

INOS

Available Sizes

Curated Selection

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