Phosphodiesterase II, Bovine Spleen
Phosphodiesterase II (EC 3.1.16.1), namely phosphodiesterase 2, is mainly involved in the hydrolysis of the important second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), and is often used in biochemical research. Phosphodiesterase II is expressed in a variety of tissues, such as the adrenal medulla, brain, heart, platelets, macrophages and endothelial cells, and is involved in the regulation of many different intracellular processes[1].
Product Specifications
CAS Number
[9068-54-6]
Product Name Alternative
3′-Exonuclease
UNSPSC
12352204
Hazard Statement
H334
Target
Phosphodiesterase (PDE)
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/phosphodiesterase-ii-bovine-spleen.html
Solubility
10 mM in DMSO
Smiles
[PhosphodiesteraseII,BovineSpleen]
Precautions
P261-P284-P304+P340-P501
References & Citations
[1]Chong Zhang, et al. The roles of phosphodiesterase 2 in the central nervous and peripheral systems. Curr Pharm Des. 2015;21 (3) :274-90.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported
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