N-Boc-trans-4-fluoro-L-proline
N-Boc-trans-4-fluoro-L-proline is a non-natural amino acid substitute used to construct monoclonal antibodies that specifically target the seed conformation of tau protein[1].
Product Specifications
CAS Number
[203866-14-2]
UNSPSC
12352209
Hazard Statement
H315, H319, H335
Target
Drug Intermediate
Type
Peptides
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/n-boc-trans-4-fluoro-l-proline.html
Purity
98.0
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(N1[C@H](C(O)=O)C[C@@H](F)C1)OC(C)(C)C
Molecular Formula
C10H16FNO4
Molecular Weight
233.24
Precautions
H315, H319, H335
References & Citations
[1]Hitt BD, et al. Anti-tau antibodies targeting a conformation-dependent epitope selectively bind seeds. J Biol Chem. 2023 Nov;299 (11) :105252.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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