S-Hexylglutathione

S-Hexylglutathione is an S-substituted glutathione in which the hydrogen of the thiol has been replaced by a hexyl group. S-Hexylglutathione is also an competitive inhibitor against glutathione-S-transferase. S-Hexylglutathione can be used as an affinity chromatographic ligand for glutathione-S-transferase and glutathione peroxidase[1][2].

Product Specifications

CAS Number

[24425-56-7]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Glutathione S-transferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/s-hexylglutathione.html

Purity

99.94

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC(CNC([C@H](CSCCCCCC)NC(CC[C@H](N)C(O)=O)=O)=O)=O

Molecular Formula

C16H29N3O6S

Molecular Weight

391.48

Precautions

H302, H315, H319, H335

References & Citations

[1]Ortiz-Salmerón E, et al. Thermodynamic description of the effect of the mutation Y49F on human glutathione transferase P1-1 in binding with glutathione and the inhibitor S-hexylglutathione. J Biol Chem. 2003 Nov 21;278 (47) :46938-48. |[2]Swope MD, et al. Macrophage migration inhibitory factor interactions with glutathione and S-hexylglutathione. J Biol Chem. 1998 Jun 12;273 (24) :14877-84.