Osimertinib (mesylate) (Standard)
Osimertinib (mesylate) (Standard) is the analytical standard of Osimertinib (mesylate) . This product is intended for research and analytical applications. Osimertinib mesylate (AZD9291 mesylate) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer[1].
Product Specifications
CAS Number
1421373-66-1
Product Name Alternative
AZD-9291 (mesylate) (Standard) ; Mereletinib (mesylate) (Standard)
UNSPSC
12352005
Target
EGFR; Reference Standards
Type
Reference Standards
Related Pathways
JAK/STAT Signaling; Others; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/osimertinib-mesylate-standard.html
Purity
99.93
Smiles
C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O.CS(=O)(O)=O
Molecular Formula
C29H37N7O5S
Molecular Weight
595.71
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed and dry storage, away from light and moisture
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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