Hematoxylin
Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
Product Specifications
CAS Number
517-28-2
Product Name Alternative
Natural Black 1; Haematoxylin
UNSPSC
12171500
Hazard Statement
H319, H402
Target
Amyloid-β
Type
Dye Reagents
Related Pathways
Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Hematoxylin.html
Concentration
10mM
Purity
99.40
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 6.67 mg/mL (ultrasonic)
Smiles
OC1=CC=C([C@]2([H])[C@](CC3=C2C=C(O)C(O)=C3)(O)CO4)C4=C1O
Molecular Formula
C16H14O6
Molecular Weight
302.28
Precautions
H319, H402
References & Citations
[1]M Titford. The long history of hematoxylin. Biotech Histochem. Mar-Apr 2005;80 (2) :73-8.|[2]Yilong Tu, et al. Hematoxylin Inhibits Amyloid β-Protein Fibrillation and Alleviates Amyloid-Induced Cytotoxicity. J Phys Chem B. 2016 Nov 10;120 (44) :11360-11368.|[3]Ada T Feldman, et al. Tissue processing and hematoxylin and eosin staining. Methods Mol Biol. 2014;1180:31-43.|[4]Robert D Cardiff, et al. Manual hematoxylin and eosin staining of mouse tissue sections. Cold Spring Harb Protoc. 2014 Jun 2;2014 (6) :655-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
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