RC574
RC574 is a novel probucol analog with the activity to protect mouse hippocampal cells and primary cortical neurons from glutamate-induced oxidative cell death (ferroptosis) and increase glutathione peroxidase (GPx) 1 levels and activity.
Product Specifications
CAS Number
[2584411-87-8]
UNSPSC
12352005
Target
Ferroptosis; Glutathione Peroxidase
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rc574.html
Smiles
OC1=C(C(C)(C)C)C=C([Se]C2=CC=CS2)C=C1C(C)(C)C
Molecular Formula
C18H24OSSe
Molecular Weight
367.41
References & Citations
[1]New Probucol Analogues Inhibit Ferroptosis, Improve Mitochondrial Parameters, and Induce Glutathione Peroxidase in HT22 Cells
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
GPX1
Available Sizes
Curated Selection
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