Fomesafen
Fomesafen is an orally active herbicide. Fomesafen inhibits protoporphyrinogen oxidase (PPO) . Fomesafen induces Apoptosis and increases ROS. Fomesafen exhibits developmental toxicity, immunotoxicity, and neurotoxicity. It induces precancerous lesions in the liver and hepaturoporphyria in mice. Fomesafen is used to control broadleaf weeds in soybean fields, rubber plantations, and orchards[1][2][3][4][5][6].
Product Specifications
CAS Number
72178-02-0
UNSPSC
12352005
Hazard Statement
H302
Target
Apoptosis; Herbicide; Protoporphyrinogen IX oxidase; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fomesafen.html
Concentration
10mM
Purity
99.81
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NS(=O)(C)=O)C1=CC(OC2=CC=C(C(F)(F)F)C=C2Cl)=CC=C1[N+]([O-])=O
Molecular Formula
C15H10ClF3N2O6S
Molecular Weight
438.76
Precautions
H302
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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